Icatibant

Last Updated: 02/24/2026

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2 clinical trials found

    Prevention of Intradialytic Hypotension by Inhibiting Bradykinin B2 Receptor A Randomized, Double-blind, Placebo-controlled, Cross Over Explorative Study

    Prevention of Intradialytic Hypotension by Inhibiting Bradykinin B2 Receptor A Randomized, Double-blind, Placebo-controlled, Cross Over Explorative Study

    Enrollment Status: Recruiting
    Publish Date: January 09, 2025
    Intervention Type: Drug
    Study Phase: Phase 3

    Summary: Currently, there is no medication available to adequately treat patients undergoing hemodialysis who are suffering from intradialytic hypotension (IDH). Medical interventions such as Trendelenburg positioning, saline bolus administration, reduction of ultrafiltration rate, interruption of the hemodialysis, and other medical treatments are the methods of choice to treat the hypotensive condition of...

    I-SPY COVID TRIAL: An Adaptive Platform Trial to Reduce Mortality and Ventilator Requirements for Critically Ill Patients

    I-SPY COVID TRIAL: An Adaptive Platform Trial to Reduce Mortality and Ventilator Requirements for Critically Ill Patients

    Who is this study for: Adult patients with COVID-19 Infection
    Enrollment Status: Recruiting
    Publish Date: March 19, 2024
    Intervention Type: Drug, Biological
    Study Drugs: Remdesivir, Cenicriviroc, Icatibant, Pulmozyme, IC14, Celecoxib, Narsoplimab
    Study Phase: Phase 2

    Summary: The goal of this project is to rapidly screen promising agents, in the setting of an adaptive platform trial, for treatment of critically ill COVID-19 patients. In this phase 2 platform design, agents will be identified with a signal suggesting a big impact on reducing mortality and the need for, as well as duration, of mechanical ventilation.

    Showing 1-2 of 2

    Last Updated: 02/24/2026