Tolcapone
Last Updated: 04/28/2026
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2 clinical trials found
Gait Pattern Analysis in Neurological Disease
Enrollment Status: Recruiting
Publish Date: June 08, 2025
Intervention Type: Drug, Device
Summary: The purpose of this study is to investigate whether speed-dependent measures of gait can be identified in patients with neurological conditions that affect gait, particularly in subjects with parkinsonian disorders.
COMT Inhibition as a Potential Therapeutic Target Among Individuals With Comorbid Alcohol Use Disorder and Attention-Deficit/Hyperactivity Disorder
Who is this study for: Adult patients with Attention Deficit Hyperactivity Disorder
Enrollment Status: Recruiting
Publish Date: November 25, 2024
Intervention Type: Drug
Study Drug: Tolcapone
Study Phase: Phase 2
Summary: The purpose of this study is to determine whether the catechol-O-methyltransferase (COMT) inhibitor tolcapone, relative to placebo, affects response to alcohol, decision-making, brain activation associated with alcohol cue reactivity, response inhibition, and selective attention, or alcohol drinking.
Showing 1-2 of 2
Last Updated: 04/28/2026