Ethacrynate

Last Updated: 06/30/2026

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Found 2257 publications

Molecular dynamics investigation of single nucleotide polymorphism-driven variations in GSTP1 phosphorylation and substrate interaction.

Molecular dynamics investigation of single nucleotide polymorphism-driven variations in GSTP1 phosphorylation and substrate interaction.

Journal: Journal of biomolecular structure & dynamics

Published: January 22, 2026

Discovery of repurposed ethacrynic acid and its derivatives as novel TEAD inhibitors.

Discovery of repurposed ethacrynic acid and its derivatives as novel TEAD inhibitors.

Journal: European journal of medicinal chemistry

Published: August 25, 2025

Ethacrynic acid regulates gentamicin ototoxicity via the blood-labyrinth barrier.

Ethacrynic acid regulates gentamicin ototoxicity via the blood-labyrinth barrier.

Journal: Hearing research

Published: June 07, 2025

Deciphering Glutathione S-Transferase P1 Inhibition Mechanisms for Overcoming Cancer Chemoresistance: Insights From Computational Analysis.

Deciphering Glutathione S-Transferase P1 Inhibition Mechanisms for Overcoming Cancer Chemoresistance: Insights From Computational Analysis.

Journal: Proteins

Published: April 21, 2025

Improved intracochlear biopolymeric drug delivery system: an in vivo study.

Improved intracochlear biopolymeric drug delivery system: an in vivo study.

Journal: Acta oto-laryngologica

Published: November 10, 2024

Positively-charged, chalcone-hydroxypyrone hybrid ruthenium(II)-arene complexes functionalized with ethacrynic acid: Synthesis, characterizaion, and antitumor effect.

Positively-charged, chalcone-hydroxypyrone hybrid ruthenium(II)-arene complexes functionalized with ethacrynic acid: Synthesis, characterizaion, and antitumor effect.

Journal: Journal of inorganic biochemistry

Published: September 18, 2024

Differential interactions of ethacrynic acid and diethyl maleate with glutathione S-transferases and their glutathione co-factor in the house fly.

Differential interactions of ethacrynic acid and diethyl maleate with glutathione S-transferases and their glutathione co-factor in the house fly.

Journal: Pesticide biochemistry and physiology

Published: August 13, 2024

Loop diuretics inhibit kynurenic acid production and kynurenine aminotransferases activity in rat kidneys.

Loop diuretics inhibit kynurenic acid production and kynurenine aminotransferases activity in rat kidneys.

Journal: Pharmacological reports : PR

Published: July 09, 2024

Identification of glutathione transferase (GST P1) inhibitors via a high-throughput screening assay and implications as alternative treatment options for breast cancers.

Identification of glutathione transferase (GST P1) inhibitors via a high-throughput screening assay and implications as alternative treatment options for breast cancers.

Journal: PloS one

Published: May 29, 2024

In Vivo Chemical Screening in Zebrafish Embryos Identified FDA-Approved Drugs That Induce Differentiation of Acute Myeloid Leukemia Cells.

In Vivo Chemical Screening in Zebrafish Embryos Identified FDA-Approved Drugs That Induce Differentiation of Acute Myeloid Leukemia Cells.

Journal: International journal of molecular sciences

Published: May 13, 2024

Design and Synthesis of (2,3-dichloro-4-(3-(substituted Phenyl)acryloyl) phenoxy) Substituted Carboxylic Acid as Potent Glutathione-s-transferase Inhibitors, Anti-breast-cancer Agents and Enhancing Therapeutic Efficacy of Anticancer Agents.

Design and Synthesis of (2,3-dichloro-4-(3-(substituted Phenyl)acryloyl) phenoxy) Substituted Carboxylic Acid as Potent Glutathione-s-transferase Inhibitors, Anti-breast-cancer Agents and Enhancing Therapeutic Efficacy of Anticancer Agents.

Journal: Medicinal chemistry (Shariqah (United Arab Emirates))

Published: May 05, 2024

Dual approach: micellar delivery of chlorambucil prodrug with concurrent glutathione depletion and GST inhibition for enhanced anticancer activity.

Dual approach: micellar delivery of chlorambucil prodrug with concurrent glutathione depletion and GST inhibition for enhanced anticancer activity.

Journal: Nanotechnology

Published: March 13, 2024

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Last Updated: 06/30/2026