Topotecan

Last Updated: 06/30/2026

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Found 3875 publications

High-Dose Intravitreal Topotecan Combined With Focal Consolidation Therapy for Recurrent Retinal Tumors in Retinoblastoma.

High-Dose Intravitreal Topotecan Combined With Focal Consolidation Therapy for Recurrent Retinal Tumors in Retinoblastoma.

Journal: Journal of vitreoretinal diseases
Published: June 22, 2026

Paired Tumor Biopsies Reveal Spatiotemporal Myeloid Remodeling After Local Chemotherapy in Glioblastoma.

Paired Tumor Biopsies Reveal Spatiotemporal Myeloid Remodeling After Local Chemotherapy in Glioblastoma.

Journal: bioRxiv : the preprint server for biology
Published: May 25, 2026

Molecular understanding for therapeutic targeting of hypoxia in breast cancer.

Molecular understanding for therapeutic targeting of hypoxia in breast cancer.

Journal: Expert opinion on therapeutic targets
Published: May 08, 2026

Design, Synthesis and Biological Evaluation of 6H-Benzimidazo[1',2':1,2]pyrido[3,4-b]indole Derivatives as TDP1 Inhibitors: Potent Synergistic Agents with Topotecan against Cervical Cancer.

Design, Synthesis and Biological Evaluation of 6H-Benzimidazo[1',2':1,2]pyrido[3,4-b]indole Derivatives as TDP1 Inhibitors: Potent Synergistic Agents with Topotecan against Cervical Cancer.

Journal: Journal of medicinal chemistry
Published: April 21, 2026

Quercetin Enhances Topotecan Cytotoxicity in Retinoblastoma Cells Through ROS-Associated Stress and Apoptotic Signaling.

Quercetin Enhances Topotecan Cytotoxicity in Retinoblastoma Cells Through ROS-Associated Stress and Apoptotic Signaling.

Journal: Biomolecules
Published: March 27, 2026

Comparative efficacy of tarlatamab and second-line therapies in extensive-stage small cell lung cancer: A network meta-analysis.

Comparative efficacy of tarlatamab and second-line therapies in extensive-stage small cell lung cancer: A network meta-analysis.

Journal: Lung cancer (Amsterdam, Netherlands)
Published: March 10, 2026

The Influence of TDP1 Inhibitor Usnic Acid Derivative OL9-116 on the Effects of Topotecan in Human Cells.

The Influence of TDP1 Inhibitor Usnic Acid Derivative OL9-116 on the Effects of Topotecan in Human Cells.

Journal: Current issues in molecular biology
Published: February 21, 2026

Molecular Determinants of Response and Rational Drug Combinations for Antibody-Drug Conjugates (ADCs) with Topoisomerase I (TOP1) Inhibitor Payloads.

Molecular Determinants of Response and Rational Drug Combinations for Antibody-Drug Conjugates (ADCs) with Topoisomerase I (TOP1) Inhibitor Payloads.

Journal: Journal of molecular biology
Published: February 18, 2026

Adverse effects associated with intrathecal chemotherapy for leptomeningeal disease.

Adverse effects associated with intrathecal chemotherapy for leptomeningeal disease.

Journal: Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners
Published: February 17, 2026

Topoisomerase inhibitors in cervical cancer: mechanistic insights and therapeutic strategies.

Topoisomerase inhibitors in cervical cancer: mechanistic insights and therapeutic strategies.

Journal: Molecular medicine (Cambridge, Mass.)
Published: February 04, 2026

Multimodal Cytogenetic and Molecular Approach for the Detection of a Constitutional Balanced Paracentric Inversion Disrupting RB1 in an Infant With Bilateral Retinoblastoma.

Multimodal Cytogenetic and Molecular Approach for the Detection of a Constitutional Balanced Paracentric Inversion Disrupting RB1 in an Infant With Bilateral Retinoblastoma.

Journal: Genes, chromosomes & cancer
Published: January 14, 2026

TLR4 and RB1 as the Identified Lactate-Related Genes to Predict the Diagnostic Performance, Gene Regulatory Network, and Targeting Drugs in Depression.

TLR4 and RB1 as the Identified Lactate-Related Genes to Predict the Diagnostic Performance, Gene Regulatory Network, and Targeting Drugs in Depression.

Journal: Human mutation
Published: January 06, 2026
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Last Updated: 06/30/2026