Nelfinavir

Last Updated: 09/26/2026

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Found 1944 publications

Non-Canonical Binding of Nelfinavir in HIV-1 Protease Variants Reveals Structural Mechanisms of Antiretroviral Resistance.

Non-Canonical Binding of Nelfinavir in HIV-1 Protease Variants Reveals Structural Mechanisms of Antiretroviral Resistance.

Journal: Viruses

Published: May 22, 2026

Causal association and molecular mechanisms of periodontal disease and muscle wasting and atrophy: Mendelian randomization and bioinformatics analysis.

Causal association and molecular mechanisms of periodontal disease and muscle wasting and atrophy: Mendelian randomization and bioinformatics analysis.

Journal: Frontiers in genetics

Published: February 12, 2026

A Priori Design, Combinatorial Synthesis, and Assessment of an Antipackaging Peptide Against Human Immunodeficiency Virus 1: Functional Role of Unnatural Trp Mimetics and Serendipitous Discovery of a Protease Inhibitor.

A Priori Design, Combinatorial Synthesis, and Assessment of an Antipackaging Peptide Against Human Immunodeficiency Virus 1: Functional Role of Unnatural Trp Mimetics and Serendipitous Discovery of a Protease Inhibitor.

Journal: ChemMedChem

Published: December 09, 2025

Repurposing Nelfinavir: AIM2 inflammasome-associated anti-tumor effects in Glioblastoma.

Repurposing Nelfinavir: AIM2 inflammasome-associated anti-tumor effects in Glioblastoma.

Journal: Biochimica et biophysica acta. Molecular basis of disease

Published: November 20, 2025

An Overview of the Mechanisms of HPV-Induced Cervical Cancer: The Role of Kinase Targets in Pathogenesis and Drug Resistance.

An Overview of the Mechanisms of HPV-Induced Cervical Cancer: The Role of Kinase Targets in Pathogenesis and Drug Resistance.

Journal: Cancers

Published: November 06, 2025

NIBAN2/FLII/RREB1 Axis Drives Glioma Stem Cell Malignancy via TLR3 Pathway Activation.

NIBAN2/FLII/RREB1 Axis Drives Glioma Stem Cell Malignancy via TLR3 Pathway Activation.

Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Published: October 05, 2025

Betulinaldehyde Ameliorates Aβ-Induced Neurotoxicity and Cognitive Deficits by Modulating the eEF2K/eEF2 Pathway.

Betulinaldehyde Ameliorates Aβ-Induced Neurotoxicity and Cognitive Deficits by Modulating the eEF2K/eEF2 Pathway.

Journal: CNS neuroscience & therapeutics

Published: July 22, 2025

Molecular docking and dynamic simulation of marine natural products from soft coral-derived microbes against SARS-CoV-2 main protease and spike protein.

Molecular docking and dynamic simulation of marine natural products from soft coral-derived microbes against SARS-CoV-2 main protease and spike protein.

Journal: Scientific reports

Published: July 06, 2025

Darunavir analog precursors target mitochondrial metabolism in multiple myeloma and CLL.

Darunavir analog precursors target mitochondrial metabolism in multiple myeloma and CLL.

Journal: Cancer cell international

Published: June 06, 2025

Insights into Antiviral Candidates against Oropouche Virus: A Molecular Dynamics Study.

Insights into Antiviral Candidates against Oropouche Virus: A Molecular Dynamics Study.

Journal: ACS physical chemistry Au

Published: May 23, 2025

Forecasting drug resistant HIV protease evolution.

Forecasting drug resistant HIV protease evolution.

Journal: PLoS computational biology

Published: April 21, 2025

Nelfinavir triggers ferroptosis by inducing ER stress mediated downregulation of GPX4/GSH system, upregulation of NRF2/HO-1 axis, and mitochondrial impairment in hepatocellular carcinoma cells.

Nelfinavir triggers ferroptosis by inducing ER stress mediated downregulation of GPX4/GSH system, upregulation of NRF2/HO-1 axis, and mitochondrial impairment in hepatocellular carcinoma cells.

Journal: Cell death discovery

Published: April 18, 2025

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Last Updated: 09/26/2026