Nelfinavir - Latest Advances

Insights into Antiviral Candidates against Oropouche Virus: A Molecular Dynamics Study.

Journal: ACS physical chemistry Au

Published: May 23, 2025

Nelfinavir triggers ferroptosis by inducing ER stress mediated downregulation of GPX4/GSH system, upregulation of NRF2/HO-1 axis, and mitochondrial impairment in hepatocellular carcinoma cells.

Journal: Cell death discovery

Published: April 18, 2025

Harnessing p53 for targeted cancer therapy: new advances and future directions.

Journal: Transcription

Published: March 03, 2025

Repurposing of approved drugs towards Nipah virus treatment: an in silico docking, molecular dynamics simulation and a MM/GBSA approach.

Journal: In silico pharmacology

Published: February 23, 2025

Insights into the interaction mechanism of first-generation HIV-1 protease inhibitors with wild-type and mutant (D30N and L76V) enzymes through in-silico based approach.

Journal: Journal of biomolecular structure & dynamics

Published: February 17, 2025

ER-phagy mediates the anti-tumoral synergism between HDAC inhibition and chemotherapy.

Journal: Cell communication and signaling : CCS

Published: February 10, 2025

Machine learning-based identification of exosome-related biomarkers and drugs prediction in nasopharyngeal carcinoma.

Journal: Discover oncology

Published: February 05, 2025

A genetically based computational drug repurposing framework for rapid identification of candidate compounds: application to COVID-19.

Journal: medRxiv : the preprint server for health sciences

Published: January 27, 2025

'Nelfinavir sensitizes a clinically relevant chemo-radioresistant cervical cancer in-vitro model by targeting the AKT-USP15/USP11-HPV16 E6/E7 axis.

Journal: Biochemistry and biophysics reports

Published: October 29, 2024

Combating pharmaceutical folklore: No alkyl-sulfonate impurities formed during the synthesis of sulfonate salts.

Journal: Journal of pharmaceutical sciences

Published: October 22, 2024

Synergistic inhibition of HIV-1 by Nelfinavir and Epigallocatechin Gallate: A novel nanoemulsion-based therapeutic approach.

Journal: Virology

Published: October 21, 2024

Postnatal prophylaxis and the use of presumptive HIV therapy for the prevention of vertical transmission of HIV in Canada 1997-2020.

Journal: Journal of the International AIDS Society

Published: October 19, 2024

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Insights into Antiviral Candidates against Oropouche Virus: A Molecular Dynamics Study.

Insights into Antiviral Candidates against Oropouche Virus: A Molecular Dynamics Study.

Nelfinavir triggers ferroptosis by inducing ER stress mediated downregulation of GPX4/GSH system, upregulation of NRF2/HO-1 axis, and mitochondrial impairment in hepatocellular carcinoma cells.

Nelfinavir triggers ferroptosis by inducing ER stress mediated downregulation of GPX4/GSH system, upregulation of NRF2/HO-1 axis, and mitochondrial impairment in hepatocellular carcinoma cells.

Harnessing p53 for targeted cancer therapy: new advances and future directions.

Harnessing p53 for targeted cancer therapy: new advances and future directions.

Repurposing of approved drugs towards Nipah virus treatment: an in silico docking, molecular dynamics simulation and a MM/GBSA approach.

Repurposing of approved drugs towards Nipah virus treatment: an in silico docking, molecular dynamics simulation and a MM/GBSA approach.

Insights into the interaction mechanism of first-generation HIV-1 protease inhibitors with wild-type and mutant (D30N and L76V) enzymes through in-silico based approach.

Insights into the interaction mechanism of first-generation HIV-1 protease inhibitors with wild-type and mutant (D30N and L76V) enzymes through in-silico based approach.

ER-phagy mediates the anti-tumoral synergism between HDAC inhibition and chemotherapy.

ER-phagy mediates the anti-tumoral synergism between HDAC inhibition and chemotherapy.

Machine learning-based identification of exosome-related biomarkers and drugs prediction in nasopharyngeal carcinoma.

Machine learning-based identification of exosome-related biomarkers and drugs prediction in nasopharyngeal carcinoma.

A genetically based computational drug repurposing framework for rapid identification of candidate compounds: application to COVID-19.

A genetically based computational drug repurposing framework for rapid identification of candidate compounds: application to COVID-19.

'Nelfinavir sensitizes a clinically relevant chemo-radioresistant cervical cancer in-vitro model by targeting the AKT-USP15/USP11-HPV16 E6/E7 axis.

'Nelfinavir sensitizes a clinically relevant chemo-radioresistant cervical cancer in-vitro model by targeting the AKT-USP15/USP11-HPV16 E6/E7 axis.

Combating pharmaceutical folklore: No alkyl-sulfonate impurities formed during the synthesis of sulfonate salts.

Combating pharmaceutical folklore: No alkyl-sulfonate impurities formed during the synthesis of sulfonate salts.

Synergistic inhibition of HIV-1 by Nelfinavir and Epigallocatechin Gallate: A novel nanoemulsion-based therapeutic approach.

Synergistic inhibition of HIV-1 by Nelfinavir and Epigallocatechin Gallate: A novel nanoemulsion-based therapeutic approach.

Postnatal prophylaxis and the use of presumptive HIV therapy for the prevention of vertical transmission of HIV in Canada 1997-2020.

Postnatal prophylaxis and the use of presumptive HIV therapy for the prevention of vertical transmission of HIV in Canada 1997-2020.