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Last Updated: 10/31/2025
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Found 186 publications
Hypophosphatasia - Pathophysiological understanding, preclinical data looking beyond the skeleton, and upcoming treatments.
Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Published: August 14, 2025
Targeted Alkaline Phosphatase Therapy Enhances Alveolar Bone Healing in X-Linked Hypophosphatemia in Mice.
Journal: Journal of periodontal research
Published: June 20, 2025
ENPP1 inhibition as a therapeutic approach for later-onset hypophosphatasia.
Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Published: May 28, 2025
Hypophosphatasia in childhood: Diagnosis to management.
Journal: Osteoporosis and sarcopenia
Published: April 25, 2025
Key Learnings from Clinical Research and Real-World Evidence on Asfotase Alfa Effectiveness in Hypophosphatasia: 10 Years Post-Approval.
Journal: Advances in therapy
Published: April 04, 2025
Effectiveness and safety of asfotase alfa for people with hypophosphatasia: a plain language summary of three studies.
Journal: Journal of comparative effectiveness research
Published: March 20, 2025
Hypophosphatasia: the importance of knowing in advance.
Journal: Minerva endocrinology
Published: March 11, 2025
Improvements in Bone Disorganization and Pseudo-Fracture Healing in Hypophosphatasia Following Asfotase Alfa Therapy May Be Detectable by the ALIGNOGRAM Before Changes in Bone Radiography or Scintigraphy.
Journal: Case reports in endocrinology
Published: March 06, 2025
Case Report: Suboptimal response to standard-dose asfotase alfa in perinatal hypophosphatasia indicates a need for individualized dosing.
Journal: Frontiers in endocrinology
Published: March 05, 2025
Medical Management of Hypophosphatasia: Review of Data on Asfotase Alfa.
Journal: Current osteoporosis reports
Published: February 17, 2025
Last Updated: 10/31/2025