Avacopan - Latest Advances

Damaged glomeruli in proliferative pediatric lupus nephritis exhibit a C5a-C5aR1 induced fibrotic transcriptional program.

Journal: bioRxiv : the preprint server for biology

Published: April 10, 2026

Extrarenal Disease in ANCA-Associated Vasculitis: Challenges and Evolving Therapeutic Strategies on behalf of the Immunonephrology Working Group (IWG) of the ERA.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association

Published: March 31, 2026

Advances in the treatment of antineutrophil cytoplasmic antibody associated vasculitis: current recommendations, clinical trials and real word data.

Journal: Polish archives of internal medicine

Published: March 12, 2026

Systemic vasculitis: one year in review 2026.

Journal: Clinical and experimental rheumatology

Published: February 27, 2026

Regression of a Refractory Pulmonary Lesion in Granulomatosis with Polyangiitis Following the Addition of Avacopan.

Journal: European journal of rheumatology

Published: February 27, 2026

Practical Considerations for Infection Prevention with the Clinical Use of Complement Inhibitors.

Journal: Clinical journal of the American Society of Nephrology : CJASN

Published: February 06, 2026

The free fatty acid 2 receptor regulates C5a induced neutrophil superoxide production and its sensitivity to inhibition by the antagonist avacopan.

Journal: Frontiers in immunology

Published: January 25, 2026

Selective Complement Inhibition in Anti-p200 Pemphigoid: Immune Infiltrate Profiles and Therapeutic Implications Compared to Bullous Pemphigoid.

Journal: Biomolecules

Published: January 06, 2026

Complement and inflammasome crosstalk in chronic inflammation.

Journal: Frontiers in immunology

Published: December 31, 2025

Update on antineutrophil cytoplasmic antibody vasculitis.

Journal: Current opinion in nephrology and hypertension

Published: December 29, 2025

Correction: Efficacy and safety of avacopan in the treatment of ANCA-associated vasculitis: a systematic review and meta-analysis.

Journal: BMC rheumatology

Published: December 24, 2025

Predictors of glucocorticoid-free clinical remission in patients with newly diagnosed microscopic polyangiitis and granulomatosis with polyangiitis: a retrospective cohort study using a nationwide registry in Japan (J-CANVAS).

Journal: Arthritis research & therapy

Published: November 29, 2025