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Last Updated: 10/31/2025

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Found 50 publications

Repurposing nirogacestat, a gamma secretase enzyme inhibitor in desmoid tumors.

Repurposing nirogacestat, a gamma secretase enzyme inhibitor in desmoid tumors.

Journal: Future oncology (London, England)
Published: September 01, 2025

New onset hidradenitis suppurativa and eruptive milia associated with gamma secretase inhibitor therapy in a patient with desmoid tumor: A case report.

New onset hidradenitis suppurativa and eruptive milia associated with gamma secretase inhibitor therapy in a patient with desmoid tumor: A case report.

Journal: JAAD case reports
Published: August 11, 2025

Top advances of the year: Sarcoma.

Top advances of the year: Sarcoma.

Journal: Cancer
Published: June 29, 2025

Management of Desmoid Tumors.

Management of Desmoid Tumors.

Journal: Current oncology reports
Published: June 12, 2025

Clinical Challenges and Evolving Treatments in Desmoid Fibromatosis: A Single Institution Experience.

Clinical Challenges and Evolving Treatments in Desmoid Fibromatosis: A Single Institution Experience.

Journal: Cancer investigation
Published: April 21, 2025

UPLC-LCMS-Based Method Development, Validation, Forced Degradation, and Impurity Profiling of Nirogacestat Drug Substance.

UPLC-LCMS-Based Method Development, Validation, Forced Degradation, and Impurity Profiling of Nirogacestat Drug Substance.

Journal: Current topics in medicinal chemistry
Published: April 16, 2025

Exploring Clinical Studies and the FDA Adverse Event Reporting System (FAERS) Database for nirogacestat-related Adverse Events.

Exploring Clinical Studies and the FDA Adverse Event Reporting System (FAERS) Database for nirogacestat-related Adverse Events.

Journal: Therapeutic innovation & regulatory science
Published: April 12, 2025

Dermatologic adverse events associated with gamma secretase inhibitor nirogacestat: A retrospective multicenter cohort study.

Dermatologic adverse events associated with gamma secretase inhibitor nirogacestat: A retrospective multicenter cohort study.

Journal: Journal of the American Academy of Dermatology
Published: March 15, 2025

A study to learn if nirogacestat works and is safe for adult participants with desmoid tumors: a plain language summary of the DeFi study.

A study to learn if nirogacestat works and is safe for adult participants with desmoid tumors: a plain language summary of the DeFi study.

Journal: Future oncology (London, England)
Published: March 12, 2025

Hidradenitis secondary to nirogacestat, a recently approved desmoid tumor medication.

Hidradenitis secondary to nirogacestat, a recently approved desmoid tumor medication.

Journal: JAAD case reports
Published: February 07, 2025

Pharmacological aspects of FDA-approved novel drug therapies against cancer in 2023: a comprehensive review.

Pharmacological aspects of FDA-approved novel drug therapies against cancer in 2023: a comprehensive review.

Journal: Naunyn-Schmiedeberg's archives of pharmacology
Published: February 05, 2025

Emerging treatments for sarcoma: from 2024 onward.

Emerging treatments for sarcoma: from 2024 onward.

Journal: Expert opinion on emerging drugs
Published: January 28, 2025
Showing 1-12 of 50

Last Updated: 10/31/2025