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          Last Updated: 01/07/2026

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          4 clinical trials found

            Low Dose Danazol for the Treatment of Telomere Related Diseases

            Background: DNA is a structure in the body. It contains data about how the body develops and works. Telomeres are found on the end of chromosomes in DNA. Some people with short telomeres or other gene changes can develop diseases of the bone marrow, lung, and liver. Researchers want to see if low doses of the hormone drug danazol can help.

            A Phase II Single Center Single Arm Pilot Study Administering Danazol for Treatment of Cytopenias in Patients With Cirrhosis

            Summary: This is a phase II pilot study designed to assess the safety and efficacy of danazol for treatment of cytopenias in patients with CPC A/B cirrhosis. Subjects with or without telomere mutations and/or shortened telomeres will be treated with danazol 600 mg per day by mouth for a duration of 24 months. The goal will be to treat a total of 10 patients.

            Far Eastern Memorial Hospital

            Summary: The aim of this study is to evaluate the efficacy between dienogest and danazol.

            Showing 1-4 of 4

            Last Updated: 01/07/2026