Ensifentrine

Last Updated: 09/26/2026

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Found 82 publications

Lung Function and Safety Outcomes in Patients With Moderate-to-Severe COPD Treated With Ensifentrine: A Pooled Analysis of the ENHANCE Trials.

Lung Function and Safety Outcomes in Patients With Moderate-to-Severe COPD Treated With Ensifentrine: A Pooled Analysis of the ENHANCE Trials.

Journal: CHEST pulmonary

Published: August 04, 2026

Summary of Research: Ensifentrine, a Novel Phosphodiesterase 3 and 4 Inhibitor for the Treatment of Chronic Obstructive Pulmonary Disease: Randomized, Double-Blind, Placebo-Controlled, Multicenter Phase III Trials (the ENHANCE Trials).

Summary of Research: Ensifentrine, a Novel Phosphodiesterase 3 and 4 Inhibitor for the Treatment of Chronic Obstructive Pulmonary Disease: Randomized, Double-Blind, Placebo-Controlled, Multicenter Phase III Trials (the ENHANCE Trials).

Journal: Advances in therapy

Published: March 24, 2026

The discovery and development of ensifentrine: A novel inhaled dual PDE3/4 inhibitor having 'bifunctional' bronchodilator and anti-inflammatory activity.

The discovery and development of ensifentrine: A novel inhaled dual PDE3/4 inhibitor having 'bifunctional' bronchodilator and anti-inflammatory activity.

Journal: British journal of pharmacology

Published: March 24, 2026

Acute Exacerbation of Chronic Obstructive Pulmonary Disease: Pharmacological Treatment of AECOPD New Perspectives.

Acute Exacerbation of Chronic Obstructive Pulmonary Disease: Pharmacological Treatment of AECOPD New Perspectives.

Journal: Seminars in respiratory and critical care medicine

Published: March 17, 2026

Natural PDE4 inhibitors from plants: A comprehensive review of discovery, structure-activity relationships, and clinical translation potential.

Natural PDE4 inhibitors from plants: A comprehensive review of discovery, structure-activity relationships, and clinical translation potential.

Journal: European journal of medicinal chemistry

Published: March 02, 2026

Ensifentrine, a novel dual phosphodiesterase 3 and 4 inhibitor in the treatment of chronic obstructive pulmonary disease.

Ensifentrine, a novel dual phosphodiesterase 3 and 4 inhibitor in the treatment of chronic obstructive pulmonary disease.

Journal: JPMA. The Journal of the Pakistan Medical Association

Published: February 25, 2026

Low-dose ensifentrine exerts anti-inflammatory effects comparable to roflumilast in COPD airways.

Low-dose ensifentrine exerts anti-inflammatory effects comparable to roflumilast in COPD airways.

Journal: American journal of respiratory cell and molecular biology

Published: February 18, 2026

A Breath of Life Beyond Bronchodilation: Early Data on Hemodynamic and Functional Outcomes With Ensifentrine Nebulization in Severe COPD-associated Pulmonary Hypertension.

A Breath of Life Beyond Bronchodilation: Early Data on Hemodynamic and Functional Outcomes With Ensifentrine Nebulization in Severe COPD-associated Pulmonary Hypertension.

Journal: The open respiratory medicine journal

Published: December 24, 2025

Ensifentrine Added on to Dual Bronchodilator or Triple Therapy Demonstrates Clinically Meaningful Improvement in CAT Score in Symptomatic Patients with Chronic Obstructive Pulmonary Disease.

Ensifentrine Added on to Dual Bronchodilator or Triple Therapy Demonstrates Clinically Meaningful Improvement in CAT Score in Symptomatic Patients with Chronic Obstructive Pulmonary Disease.

Journal: International journal of chronic obstructive pulmonary disease

Published: December 23, 2025

Bronchorelaxant and anti-inflammatory profile of ensifentrine alone and combined with inhaled medications in lipopolysaccharide-challenged human airways from chronic obstructive pulmonary disease donors.

Bronchorelaxant and anti-inflammatory profile of ensifentrine alone and combined with inhaled medications in lipopolysaccharide-challenged human airways from chronic obstructive pulmonary disease donors.

Journal: The Journal of pharmacology and experimental therapeutics

Published: December 19, 2025

Ensifentrine: A Potential Shift in COPD Management.

Ensifentrine: A Potential Shift in COPD Management.

Journal: JPMA. The Journal of the Pakistan Medical Association

Published: December 11, 2025

Novel Maintenance Therapies for Chronic Obstructive Pulmonary Disorder.

Novel Maintenance Therapies for Chronic Obstructive Pulmonary Disorder.

Journal: The Annals of pharmacotherapy

Published: November 05, 2025

Showing 1-12 of 82

Last Updated: 09/26/2026