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Last Updated: 10/31/2025
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Found 101 publications
Mechanism of Action of Gepotidacin: Well-Balanced Dual-Targeting against Neisseria gonorrhoeae Gyrase and Topoisomerase IV in Cells and In Vitro.
Journal: ACS infectious diseases
Published: October 09, 2025
Efficacy and in vitro activity of gepotidacin against bacterial uropathogens, including subsets with molecularly characterized resistance mechanisms and genotypes/epidemiological clones, in females with uncomplicated urinary tract infections: results from two global, pivotal, phase 3 trials (EAGLE-2 and EAGLE-3).
Journal: Antimicrobial agents and chemotherapy
Published: September 09, 2025
Efficacy and in vitro activity of gepotidacin against bacterial uropathogens, including drug-resistant phenotypes, in females with uncomplicated urinary tract infections: results from two global, pivotal, phase 3 trials (EAGLE-2 and EAGLE-3).
Journal: Antimicrobial agents and chemotherapy
Published: September 09, 2025
In urogenital gonorrhea, gepotidacin was noninferior to ceftriaxone + azithromycin for microbiological success.
Journal: Annals of internal medicine
Published: August 04, 2025
New Era for Urinary Tract Infection Treatment: Gepotidacin Receives FDA Approval.
Journal: International urogynecology journal
Published: July 28, 2025
Gepotidacin: A Novel Antibiotic for the Treatment of Uncomplicated Urinary Tract Infections.
Journal: The Annals of pharmacotherapy
Published: June 03, 2025
Oral gepotidacin for the treatment of uncomplicated urinary tract infection in Japanese female patients: a randomized, active reference, double-blind, double-dummy, Phase 3 trial (EAGLE-J).
Journal: Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy
Published: May 30, 2025
Uncomplicated urinary tract infections: the new antibiotic gepotidacin is at least as effective as nitrofurantoin
Journal: Recenti progressi in medicina
Published: May 16, 2025
In vitro activity of gepotidacin against urinary tract infection isolates of Enterobacterales, Enterococcus faecalis, and Staphylococcus saprophyticus.
Journal: Antimicrobial agents and chemotherapy
Published: May 15, 2025
An overview of potential combination therapies with ceftriaxone as a treatment for gonorrhoea.
Journal: Expert review of anti-infective therapy
Published: May 15, 2025
Last Updated: 10/31/2025