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Last Updated: 01/07/2026
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Found 95 publications
The combination of avutometinib and defactinib in treating recurrent low-grade serous ovarian cancer: a plain language summary of the Phase II clinical trial ENGOT-OV60/GOG-3052/RAMP 201.
Journal: Future oncology (London, England)
Published: December 12, 2025
Unmet needs and emerging therapeutics in low-grade serous ovarian carcinoma: from chemoresistance to precision medicine.
Journal: Future oncology (London, England)
Published: November 05, 2025
Erratum: Efficacy and Safety of Avutometinib ± Defactinib in Recurrent Low-Grade Serous Ovarian Cancer: Primary Analysis of ENGOT-OV60/GOG-3052/RAMP 201.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Published: October 13, 2025
Transcriptional Rewiring of BET Inhibitor Treated Ewing Sarcoma Cells Augments their Dependency on Focal Adhesion Kinase.
Journal: bioRxiv : the preprint server for biology
Published: September 15, 2025
Preclinical Efficacy of the Estrogen Receptor Degrader Fulvestrant in Combination with RAF/MEK Clamp Avutometinib and FAK Inhibitor in a Low-Grade Serous Ovarian Cancer Animal Model with Acquired Resistance to Chemotherapy and Aromatase Inhibitor.
Journal: International journal of molecular sciences
Published: July 19, 2025
Avmapki Fakzynja Co-Pack for ovarian cancer.
Journal: The Medical letter on drugs and therapeutics
Published: July 12, 2025
Efficacy and Safety of Avutometinib ± Defactinib in Recurrent Low-Grade Serous Ovarian Cancer: Primary Analysis of ENGOT-OV60/GOG-3052/RAMP 201.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Published: July 11, 2025
Targeting Focal Adhesion Kinase in Lung Diseases: Current Progress and Future Directions.
Journal: Biomolecules
Published: July 01, 2025
Sensitivity of Pancreatic Cancer Cell Lines to Clinically Approved FAK Inhibitors: Enhanced Cytotoxicity Through Combination with Oncolytic Coxsackievirus B3.
Journal: International journal of molecular sciences
Published: June 19, 2025
Targeting focal adhesion kinase inhibits cell migration and non-angiogenic vascularization in malignant breast cancer.
Journal: Breast cancer (Tokyo, Japan)
Published: June 12, 2025
RhoE down-regulation leads to enhanced cholesterol biosynthesis and sorafenib resistance in hepatocellular carcinoma.
Journal: The Journal of biological chemistry
Published: June 12, 2025
Last Updated: 01/07/2026