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Last Updated: 01/07/2026
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Found 267 publications
Molecular mechanism of resistance to lonafarnib conferred by mutations in the cysteine-rich region of respiratory syncytial virus fusion glycoprotein and discovery of a lonafarnib-derived antiviral PROTAC.
Journal: Journal of virology
Published: December 09, 2025
Inhibition of farnesyltransferase activity diminishes hematopoietic stem cell ex vivo expansion ability.
Journal: bioRxiv : the preprint server for biology
Published: November 24, 2025
The Fall of the Armor: Lamin Dysregulation and a Wide Network of Laminopathies.
Journal: Sub-cellular biochemistry
Published: September 26, 2025
Discovery of Tricyclic Derivative as Novel and Potent Respiratory Syncytial Virus Fusion Glycoprotein Inhibitor with an Improved Pharmacokinetic Profile.
Journal: Journal of medicinal chemistry
Published: September 11, 2025
Lonafarnib Clinical Trials Demonstrate Uncoupling of the Muscle-Bone Unit in Hutchinson-Gilford Progeria Syndrome.
Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Published: July 29, 2025
Updates on Recent Advancements in Hepatitis D Virus Treatment.
Journal: Viruses
Published: July 24, 2025
Hepatitis Delta Virus Infection: An Overview.
Journal: Pathogens (Basel, Switzerland)
Published: July 20, 2025
Farnesyltransferase inhibitors decrease matrix-vesicle-mediated mineralization in SaOS-2 cells.
Journal: Molecular biology reports
Published: May 12, 2025
Baricitinib and Lonafarnib Synergistically Target Progerin and Inflammation, Improving Lifespan and Health in Progeria Mice.
Journal: International journal of molecular sciences
Published: April 12, 2025
Last Updated: 01/07/2026