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          Last Updated: 02/24/2026

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          1 clinical trial found

            Targeting Residual Activity By Precision, Biomarker-Guided Combination Therapies of Multiple Sclerosis (TRAP-MS)

            Targeting Residual Activity By Precision, Biomarker-Guided Combination Therapies of Multiple Sclerosis (TRAP-MS)

            Who is this study for: Patients with Multiple Sclerosis
            Enrollment Status: Recruiting
            Publish Date: February 05, 2026
            Intervention Type: Drug
            Study Drugs: Pioglitazone, Clemastine Fumarate, Hydroxychloroquine, Dantrolene
            Study Phase: Phase 1/Phase 2

            Background: In people with multiple sclerosis (MS), brain and cerebrospinal fluid (CSF) biomarkers indicate inflammation or disease. Researchers want to see if 4 drugs given alone or combined affect MS biomarkers. They want to see if a change in biomarker levels can predict which drugs a person with MS might respond to.

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            Last Updated: 02/24/2026