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          Last Updated: 10/31/2025

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          2 clinical trials found

            A Phase 3b Open-Label Study of Long-Term Neurocognitive Outcomes in Children With Phenylketonuria Treated With Sepiapterin

            Summary: The main purpose of this trial is to evaluate the long-term efficacy of sepiapterin on preserving neurocognitive functioning in children with PKU when treatment is initiated in early childhood.

            A Phase 3 Open-Label Study of PTC923 (Sepiapterin) in Phenylketonuria

            Summary: The main purpose of this study is to evaluate the long-term safety of PTC923 in participants with phenylketonuria, and to evaluate the changes from baseline in dietary phenylalanine (Phe)/protein consumption.

            Showing 1-2 of 2

            Last Updated: 10/31/2025