Fentanyl Versus Dexmedetomidine as an Adjuvant to Bupivacaine in Spinal Anaesthesia for Appendectomy Patients; Peritoneal Symptomatic Effects: A Randomized Clinical Trial
Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 3
SUMMARY
To compare whether 5 μg dexmedetomidine with 25 μg fentanyl added to 0.5% hyperbaric bupivacaine as adjuvants in spinal anaesthesia in patients undergoing appendectomy could reduce intraoperative peritoneal related symptoms.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 60
Healthy Volunteers: f
View:
• ASA physical status class I and II.
• Age between 18 - 60 years of either sex.
Locations
Other Locations
Egypt
Aswan University
RECRUITING
Aswān
Contact Information
Primary
Soudy S Hammad, MD
soudi.salah@aswu.edu.eg
+201014761523
Backup
Ahmed M Hagag, MSc
01141097536
Time Frame
Start Date: 2023-07-01
Estimated Completion Date: 2025-02-25
Participants
Target number of participants: 148
Treatments
Active_comparator: Group D (N.74)
5µg Dexmedetomidine {precedexTM 200U/2ml Hospira, Inc,lake forest,iL,USA} (5 µg added by taking 50 µg in a insulin syringe) + 4ml 0.5% heavy bupivacaine HCl.
Active_comparator: Group F (N.74) -
25 µg Fentanyl {fentanyl Hameln 50 u/ml Gmbh-germany} + 4ml 0.5% heavy bupivacaine HCl.
Related Therapeutic Areas
Sponsors
Leads: Aswan University