A Single-centre, Randomized Study to Compare the Outcomes of Protected Transverse Colostomy Versus Ileostomy After Low Anterior Resection of Low Rectal Cancer From the Perspective of Intestinal Microecology
Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
Exploring the effect of protective ileostomy compared with transverse colostomy on the occurrence of complications, the occurrence of serious side effects of adjuvant chemotherapy and disease recurrence in patients with low rectal cancer after radical surgery from the perspective of intestinal microecology.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 80
Healthy Volunteers: f
View:
• Pathological confirmed adenocarcinoma of the rectum;
• Patients age between 18-80;
• Baseline AJCC stage I-III: cT1-4N0-2M0 (AJCC-8 version);
• Eastern Cooperative Oncology Group (ECOG) physical status score of 0 to 2;
• Patients voluntarily sign informed consent.
Locations
Other Locations
China
Fudan University Shanghai Cancer Center
RECRUITING
Shanghai
Contact Information
Primary
Yanlei Ma, PhD
yanleima@fudan.edu.cn
(86)13122680635
Backup
Yichi Zhang, MD
22111230058@m.fudan.edu.cn
(86)18588731911
Time Frame
Start Date: 2023-06-23
Estimated Completion Date: 2027-05
Participants
Target number of participants: 300
Treatments
Experimental: Ileostomy
Protective ileostomy as a defunction mean after low anterior resection
Experimental: Transverse colostomy
Protective transverse colostomy as a defunction mean after low anterior resection
Related Therapeutic Areas
Sponsors
Leads: Fudan University