Prospective Study of Fertility-sparing Treatment Strategy in Patients With Early Cervical Cancer(SYSUGO-005/CSEM009)

Who is this study for? Adult but not older adult female patients with Stage IB1 to IIA2 Cervical Cancer
What treatments are being studied? Cisplatin+Radical Hysterectomy
Status: Recruiting
Location: See all (2) locations...
Intervention Type: Procedure, Drug
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Patients with cervical cancer staging IB1-IIA2 desiring keeping their fertility function will be recruited. Before treatment, MRI scanning will be used to exclude retroperitoneal lymph node metastasis, involvement of lower part of uterus and endometrial carcinoma.If there is no macroscopic tumor and no obvious disease in MRI,simple trachelectomy (ST) + sentinel lymph node biopsy (SLNB) / retroperitoneal lymph node dissection(RPLND) will be performed. Otherwise,two to three cycles of neoadjuvant chemotherapy (NACT) will be administrated and then different fertility-sparing surgery(conization,ST or radical trachelectomy(RT) + SLNB/RPLND) will be employed depending on the tumor size.

Eligibility
Participation Requirements
Sex: Female
Minimum Age: 18
Maximum Age: 40
Healthy Volunteers: f
View:

• patients with cervical cancer staging IB1-IIA2 desiring keeping their fertility function

Locations
Other Locations
China
Clinical Trial Center
RECRUITING
Guangzhou
Sun Yat-sen University Cancer Center
RECRUITING
Guangzhou
Contact Information
Primary
Yanling Feng, Doctor
fengyl@sysucc.org.cn
+862013925090579
Time Frame
Start Date: 2015-11
Estimated Completion Date: 2025-11
Participants
Target number of participants: 60
Treatments
Other: fertility-sparing surgery
NACT with Taxane combined with cisplatin and Fertility-sparing Treatment Strategy
Related Therapeutic Areas
Sponsors
Leads: Sun Yat-sen University

This content was sourced from clinicaltrials.gov