The Association Between Radiation Dermatitis and Skin Microbiome in Breast Cancer Patients Receiving Radiation After Mastectomy and Reconstructive Surgery
Status: Recruiting
Location: See location...
Intervention Type: Radiation
Study Type: Observational
SUMMARY
The breast cancer patients who received radiotherapy after mastectomy and breast reconstruction will be enrolled. The skin microbiome before radiotherapy and its changes after radiotherapy will be analyzed systematically to find out whether the skin microbiome is associated with the severity of radiation dermatitis.
Eligibility
Participation Requirements
Sex: Female
Minimum Age: 18
Maximum Age: 70
Healthy Volunteers: f
View:
• Female patients
• Invasive breast cancer confirmed by pathology
• Underwent mastectomy and breast reconstruction
• Radiotherapy after breast reconstruction
• ECOG score 0-1
• Signed informed consent
Locations
Other Locations
China
Fudan University Shanghai Cancer Center
RECRUITING
Shanghai
Contact Information
Primary
Wei Shi, MD, Ph.D
wei.shi118@foxmail.com
+86 18121299680
Backup
Li Zhang, MD
zhangliaaa111@163.com
Time Frame
Start Date: 2021-01-01
Estimated Completion Date: 2026-12-31
Participants
Target number of participants: 100
Treatments
Severe radiation dermatitis
RTOG/EORTC grade 2 and above
No or mild radiation dermatitis
RTOG/EORTC grade 0 or 1
Related Therapeutic Areas
Sponsors
Leads: Fudan University