Neoadjuvant Radiotherapy and Immediate Implant-Based Breast Reconstruction

Status: Recruiting
Location: See location...
Intervention Type: Radiation
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Neoadjuvant radiotherapy(NART) followed by mastectomy and immediate DIEP flap reconstruction is feasible and technically safe. However, reports of NACT followed immediate implant-based breast reconstruction are rare. Some studies have shown that NART followed immediate implant-based breast reconstruction seems feasible and can be safely attempted. It's well known that radiotherapy after implant-based breast reconstruction have negative effects on implant and cosmetic results. So, investigators conducted a polit study to learn about acute post-surgical complications following skin-sparing mastectomy and immediate implant-based breast reconstruction after NART.

Eligibility
Participation Requirements
Sex: Female
Minimum Age: 18
Maximum Age: 75
Healthy Volunteers: f
View:

⁃ Women \>18 years with histopathologically-confirmed breast cancer, who:

• require mastectomy for any reason

• a known indication for (adjuvant) radiotherapy

• require implant-based breast reconstruction

Locations
Other Locations
China
Xinhong Wu
RECRUITING
Wuhan
Contact Information
Primary
Xinhong Wu, MD
34053889@qq.com
+8618602726300
Backup
Ning Zou, MD
sunnyning116@163.com
+8615007162698
Time Frame
Start Date: 2023-07-08
Estimated Completion Date: 2025-10-31
Participants
Target number of participants: 40
Treatments
Experimental: Neoadjuvant radiotherapy group
Radiotherapy followed by skin-sparing mastectomy and immediate implant-based reconstruction in HBCH
Related Therapeutic Areas
Sponsors
Leads: Hubei Cancer Hospital

This content was sourced from clinicaltrials.gov