A Study on Artificial Intelligence Algorithms for Breast Cancer Classification From Histopathology Images

Status: Recruiting
Location: See location...
Intervention Type: Diagnostic test
Study Type: Observational
SUMMARY

Breast cancer, a prevalent and potentially fatal disease, underscores the need for early and accurate detection to improve patient outcomes. Traditional histopathological examination, the current gold standard for diagnosis, faces limitations like subjectivity and low efficiency. In response, this research seeks to revolutionize breast cancer diagnostics by using deep learning techniques to classify invasive and noninvasive breast cancer types from histopathological images. Non-invasive cancers, like DCIS and LCIS, are confined to milk ducts or lobules, while invasive cancers spread to surrounding tissue and make up 70% of cases, often leading to poorer outcomes. The proposed AI model aims to enhance diagnostic accuracy and efficiency, surpassing manual methods, and providing a scalable solution for diverse healthcare settings. By automating image analysis, the model seeks to democratize cancer screening, making it accessible in underserved populations and adaptable to different resources and equipment. Ultimately, this research aims to advance breast cancer detection, improve patient care, and contribute to better treatment outcomes globally.

Eligibility
Participation Requirements
Sex: Female
Healthy Volunteers: t
View:

⁃ Female patients of any age can be selected as subjects.

• Individuals willing to participate in breast cancer screening.

• Availability for biopsy examination.

• Women with no current or prior diagnosis of breast cancer.

• Availability of relevant medical records for confirmation and comparison purposes.

Locations
Other Locations
Bangladesh
National Institute of Cancer Research & Hospital (NICRH)
RECRUITING
Dhaka
Contact Information
Primary
Taufiq Hasan, PhD
taufiq@bme.buet.ac.bd
+8801817579844
Backup
Samiha Jainab, B.Sc.
jainab.samiha@gmail.com
+8801914556073
Time Frame
Start Date: 2024-01-11
Estimated Completion Date: 2025-02-11
Participants
Target number of participants: 500
Treatments
Women who undergo biopsy for suspected abnormal cell growth in the breast
The cohort includes women who have undergone a biopsy due to suspected abnormal cell growth in the breast. This cohort captures a wide range of potential diagnoses, including benign conditions, noninvasive (in situ) breast cancers, and invasive breast cancers. All participants have histopathological samples collected for analysis, which serve as the basis for determining the presence and type of abnormal cell growth. The cohort will be studied using deep learning techniques to classify the biopsy samples into specific categories (normal, benign, in situ, or invasive), with the goal of improving diagnostic accuracy and efficiency in detecting breast cancer.~By focusing on women undergoing biopsy, this study aims to address the diagnostic challenges faced in distinguishing between various breast tissue abnormalities, contributing to earlier detection and better clinical outcomes.
Related Therapeutic Areas
Sponsors
Leads: Taufiq Hasan, PhD
Collaborators: National Institute of Cancer Research & Hospital, Bangladesh

This content was sourced from clinicaltrials.gov