Analgesic Efficacy of Rhomboid Intercostal Block With Sub-Serratus Plane Block Versus Erector Spinae Block in Breast Cancer Surgery

Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

This study compares two nerve block techniques-Rhomboid Intercostal with Sub-Serratus Plane Block versus Erector Spinae Plane Block-for pain relief after breast cancer surgery. It aims to determine which method provides better postoperative pain control, reduces opioid use, and improves recovery in patients undergoing modified radical mastectomy at the National Cancer Institute, Cairo University.

Eligibility
Participation Requirements
Sex: Female
Minimum Age: 18
Maximum Age: 65
Healthy Volunteers: f
View:

• Female breast cancer patients undergoing Modified Radical Mastectomy (MRM)

⁃ ASA physical status II or III

⁃ Age between 18 and 65 years

⁃ Body Mass Index (BMI) \> 20 kg/m² and \< 35 kg/m²

Locations
Other Locations
Egypt
National Cancer Institute - Cairo University
RECRUITING
Cairo
Contact Information
Primary
Sayed Mahmoud M Abed, MD
sayed.abed@nci.cu.edu.eg
+20 122 680 6532
Time Frame
Start Date: 2025-06-01
Estimated Completion Date: 2026-07-01
Participants
Target number of participants: 80
Treatments
Experimental: Rhomboid Intercostal Block with Sub-Serratus Plane Block
Participants in this group will receive ultrasound-guided Rhomboid Intercostal Block (20 mL of 0.25% bupivacaine between rhomboid major and intercostal space) followed by Sub-Serratus Plane Block (20 mL of 0.25% bupivacaine between serratus anterior and ribs) 30-45 minutes before general anesthesia for Modified Radical Mastectomy.
Active_comparator: Erector Spinae Plane Block
Participants in this group will receive an ultrasound-guided Erector Spinae Plane Block with 30 mL of 0.25% bupivacaine injected into the paraspinal plane at the T4-T5 level, 30-45 minutes prior to general anesthesia for Modified Radical Mastectomy.
Related Therapeutic Areas
Sponsors
Leads: Cairo University

This content was sourced from clinicaltrials.gov