The SEQUENCE Trial: Should Endobronchial Ultrasound QUeue bEfore or eNsuing to robotiC-assisted Bronchoscopy for pEripheral Pulmonary Nodule Biopsy?
Status: Recruiting
Location: See all (5) locations...
Intervention Type: Diagnostic test
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
This study will randomize participants undergoing a bronchoscopic biopsy of a peripheral pulmonary nodule for their standard of care to receive robotic-assisted bronchoscopy (RaB) and then staging linear endobronchial ultrasounnd (EBUS) OR staging linear EBUS first, followed by RaB. The goal of this study is to set the standard for optimizing the sequence of bronchoscopic procedures in patients at risk for early-stage malignancy.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: t
View:
• Peripheral Pulmonary Nodule undergoing a robotic-assisted bronchoscopy
Locations
United States
California
University of California, Davis
RECRUITING
Sacramento
Illinois
Northwestern University
RECRUITING
Chicago
Maryland
Johns Hopkins University
RECRUITING
Baltimore
Michigan
University of Michigan
RECRUITING
Ann Arbor
North Carolina
University of North Carolina, Chapel Hill
RECRUITING
Chapel Hill
Contact Information
Primary
Chris Kapp Assistant professor of medicine, MD
christopher.kapp@nm.org
312-695-3800
Time Frame
Start Date: 2024-11-10
Estimated Completion Date: 2027-12
Participants
Target number of participants: 320
Treatments
Active_comparator: Linear EBUS First
Patients will undergo a mediastinal lymph node evaluation with EBUS first, followed by biopsy followed by robotic-assisted bronchoscopy
Active_comparator: Robotic-assisted bronchoscopy first
Patients will undergo a robotic-assisted bronchoscopy first, followed by a mediastinal lymph node evaluation with EBUS second
Related Therapeutic Areas
Sponsors
Collaborators: University of California, San Diego, University of Michigan, Johns Hopkins University, University of California, Davis, University of North Carolina, Chapel Hill
Leads: Northwestern University