Transcatheter Aortic Valve Replacement With Echocardiography Guidance

Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY

Conventional transcatheter aortic valve replacement (TAVR) relies on fluoroscopic and contrast agents. However, in high-risk patients, exposure to ionizing radiation and contrast agents is contraindicated and undesirable. Echocardiography guidance TAVR can offer a feasible and safer strategy for TAVR.

Eligibility
Participation Requirements
Sex: All
Healthy Volunteers: f
View:

• symptomatic severe AS determined by echocardiography and Doppler that requiring aortic valve replacement, which is defined as: mean gradient ≥40 mmHg, peak aortic velocity ≥4 m/s, and aortic valve area (AVA) ≤1 cm2 (or an indexed AVA ≤0.6 cm2/m2);

• a history of malignancy or a high familial risk of cancer, with refusal to undergo contrast- or radiation-guided procedures;

• chronic kidney disease and refuse to receive contrast agents or radiation exposure.

Locations
Other Locations
China
Fuwai Hospital
RECRUITING
Beijing
Contact Information
Primary
Xiangbin Pan, MD
panxiangbin@fuwaihospital.org
88396655
Backup
Fengwen Zhang, MD
88396654
Time Frame
Start Date: 2025-02-18
Estimated Completion Date: 2025-12-31
Participants
Target number of participants: 20
Sponsors
Leads: Pan Xiangbin

This content was sourced from clinicaltrials.gov

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