Effectiveness of Sugammadex Versus Neostigmine on Neuromuscular Reversal in Pediatric Patients Undergoing Laparoscopic Appendectomy for Acute Appendicitis: A Randomized Controlled Trial
Status: Terminated
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 4
SUMMARY
This study is designed as a randomized controlled trial with patients assigned to neuromuscular reversal with either sugammadex or neostigmine/glycopyrrolate reversal. The study will not be blinded to the anesthesiologist to allow for appropriate decision-making on timing and dosage of reversal. This is a single-center study.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 2
Maximum Age: 17
Healthy Volunteers: f
View:
• Patients 2-17 years of age
• Diagnosis of acute appendicitis
• Patient undergoing laparoscopic appendectomy at Children's Healthcare of Atlanta- Egleston.
• Parent or Legal Authorized Representative willing to participate, able to understand and sign an informed consent
Locations
United States
Georgia
Children's Healthcare of Atlanta
Atlanta
Time Frame
Start Date: 2023-07-19
Completion Date: 2024-08-05
Participants
Target number of participants: 22
Treatments
Experimental: Sugammadex
The reversal agent, Sugammadex, will be administered at the start of closure.
Active_comparator: Neostigmine/Glycopyrrolate
The reversal agent, Neostigmine, will be administered at the start of closure.
Related Therapeutic Areas
Sponsors
Leads: Emory University