STOPS Trial: A Multicentre Prospective Randomised Clinical Trial Comparing Total Colectomy With Ileorectal Anastomosis Versus Subtotal Colectomy With Cecal-rectal Anastomosis for Slow Transit Constipation
Total colectomy with ileorectal anastomosis is a traditional surgical option for slow transit constipation (STC). Subtotal colectomy with caecorectal anastomosis have been reported to be a potential alternative approach. Thus, the optimal surgical option for STC is controversial.
• Patients (≥18 years of age) of either sex
• Patients with conditions in agreement with the Roman IV criteria of functional constipation
• Patients have less than one complete spontaneous bowel movement per week
• Patients rely on laxatives to assist defecation for a long time
• More than 20% the radio-paque markers localized in the colon after 72 hours based on colonic transit studies
• Patients were refractory to conservative treatment for more than 1 year
• Patients with a strong desire for surgery