Enhanced Recovery Protocol for Acute, Complicated Appendicitis After Laparoscopic Appendectomy: An Exploratory Pilot Study

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The exploratory objective of this pilot study is to evaluate the feasibility and safety of an enhanced recovery protocol that will allow adult patients to be discharged to home on an oral antibiotic regimen for three days following a laparoscopic appendectomy for complicated appendicitis. Feasibility will be determined by high compliance and adherence of patients to the postoperative instructions, while safety will be assessed by the incidence of postoperative infectious complications and requirement for re-admission.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
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• Individuals between the ages of 18 and 65 years of age.

• Patients undergoing a laparoscopic appendectomy.

• Diagnosis of complicated appendicitis based on pre-operative imaging or intra-operative assessment. The definition of a complicated appendicitis will include: (a) perforated appendicitis, without generalized peritonitis; (b) gangrenous appendicitis, without generalized peritonitis; (c) suppurative appendicitis; (d) iatrogenic perforation of the appendix.

• Meet criteria for discharge from the post-anesthesia care unit (PACU).

• Ability to reliably follow up with the study procedures.

Locations
United States
California
Cedars-Sinai Medical Center
RECRUITING
Los Angeles
Contact Information
Primary
Laura Sarmiento, CCRP
laura.sarmiento@cshs.org
310-423-4295
Time Frame
Start Date: 2025-04-21
Estimated Completion Date: 2026-02-28
Participants
Target number of participants: 20
Treatments
Other: ERAS
Patients with intraoperative diagnosis of complicated appendicitis as determined by the operating surgeon.
Sponsors
Leads: Cedars-Sinai Medical Center

This content was sourced from clinicaltrials.gov