Randomized Trial of Orbital Atherectomy Versus Standard Strategy in Calcified Bifurcation Lesions

Status: Recruiting
Location: See all (2) locations...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Clinical research with medical devices indicated in accordance with the CE marking, led by researchers, multicenter, open, prospective, randomized and controlled. Patients are randomized to treatment with a conventional balloon and then a coronary stent or to initial plaque modification with Orbital Atherectomy (OA) and then a coronary stent. To evaluate the efficacy and safety of OA in the adequate treatment with coronary stent of the calcified bifurcation lesion using angiography and optical coherence tomography (OCT).

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Patients over 18 years of age and

• Patients with moderately or severely calcified bifurcation lesions (lateral vessel ≥ 2mm), candidates for PCI with coronary stent implantation, in whom there is the possibility of adequate clinical follow-up at 1 year and

• Patients agree to participate in the study, by signing the Informed Consent.

Locations
Other Locations
Spain
H. G.U. de ALICANTE DR. BALMIS
RECRUITING
Alicante
Hospital Universitario Lucus Augusti
RECRUITING
Lugo
Contact Information
Primary
JORGE PALAZUELOS, MD, PhD
jpalaz@gmail.com
0034659768506
Backup
FUNDACION EPIC
iepic@fundacionepic.org
0034987876135
Time Frame
Start Date: 2025-10-23
Estimated Completion Date: 2026-12-31
Participants
Target number of participants: 200
Treatments
Active_comparator: Balloon Angioplasty (BA)
Active_comparator: Orbital Atherectomy (OA)
Sponsors
Leads: Fundación EPIC

This content was sourced from clinicaltrials.gov