Bone Graft Clinical Trials

Clinical trials related to Bone Graft Procedure

L-PRF Versus Sticky Bone Grafting of the Jumping Gap in AI-assisted/Computer-Guided Socket Shield Immediate Dental Implantation: A Randomized Clinical Trial

Status: Recruiting
Location: See all (2) locations...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

the rationale of the current study is to address a focused and clinically relevant gap in socket shield therapy: which biologic modality best supports healing of the shield-implant gap when SST is performed under a standardized, digitally guided workflow. The study will compare three shield-implant gap filling modalities: (i) L-PRF alone (without membrane), (ii) sticky tooth (autogenous dentin graft +i- PRF), and (iii) sticky bone (particulate graft + i- PRF) under AI-assisted, patient-specific guided implant placement based on IOS/CBCT superimposition, with CBCT follow-up at immediate, 3 months, and 6 months. The working hypothesis is that biologically active, cohesive composites (sticky tooth and sticky bone) will provide superior hard- and soft-tissue dimensional stability compared with PRF alone by improving space maintenance and early wound stability in the shield-implant gap . The null hypothesis is that there will be no statistically significant differences between the three modalities in radiographic and digitally assessed clinical outcomes over the 6-month follow-up period .

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 45
Healthy Volunteers: t
View:

• Medically healthy patients according to the American Society of Anesthesiologists (ASA) physical status classification system; only patients belonging to ASA I and ASA II categories will be included in this study.

• Age \> 18 years.

• Patients presenting with one non-restorable hopeless anterior tooth due to extensive caries, cervical/root fracture, vertical or oblique root fracture, multiple failed endodontic treatments, or root resorption.

• Sufficient apical/palatal bone to obtain primary implant stability.

Locations
Other Locations
Egypt
faculty of dentistry, kafrelsheikh University
RECRUITING
Kafr Ash Shaykh
Walid Elamrousy
RECRUITING
Kafr Ash Shaykh
Contact Information
Primary
Walid Elamrousy, PhD
waled_hammed@den.kfs.edu.eg
+201029552024
Backup
Nour Hatata, Phd
+2025170737
Time Frame
Start Date: 2026-02-23
Estimated Completion Date: 2027-03-28
Participants
Target number of participants: 45
Treatments
Active_comparator: PRF alone group
Immediately after implant placement, leukocyte-platelet rich fibrin (L-PRF) will be prepared, then gently packed into the implant-shield gap
Experimental: Sticky tooth group
The extracted palatal root portion will be cleaned and processed chairside into dentin particles, then mixed with PRF clot to form sticky tooth that will be packed into the implant-shield gap
Experimental: Sticky bone group
xenograft will be mixed with PRF clot to form sticky bone that will be packed into the implant-shield gap
Related Therapeutic Areas
Sponsors
Leads: Kafrelsheikh University

This content was sourced from clinicaltrials.gov

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