Systematic Light Exposure Effects on Circadian Rhythms Entrainment, Inflammation, Neutropenic Fever and Symptom Burden Among Multiple Myeloma Patients Undergoing Autologous Stem Cell Transplantation

Status: Recruiting
Location: See all (2) locations...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The aim of this multi-site randomized control trial will be is to assess the impact Systematic lighting on circadian rhythm entrainment, Inflammation, Neutropenic Fever and Symptom Burden among Multiple Myeloma Patients undergoing Autologous Stem Cell Transplantation. To achieve this aim, 200 multiple myeloma patients will receive one of two different light-treatments that are designed to promote circadian rhythm alignment. While receiving these light treatments, participants' sleep efficiency, urine melatonin levels, blood inflammatory cytokine levels and symptoms will be assessed over a 2-month period.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 21
Healthy Volunteers: f
View:

• Multiple Myeloma diagnosis

• Scheduled to undergo their first Autologous Stem Cell Transplant procedure.

• 21years or older

• Able to provide informed consent.

• English-language proficient

Locations
United States
New York
Icahn Schoool of Medicine at Mount Sinai
RECRUITING
New York
Memorial Sloan Kettering Cancer Center
RECRUITING
New York
Contact Information
Primary
Barbara Plitnick, BSN
Barbara.Plitnick@mountsinai.org
518 242-4603
Backup
Mariana Figueiro, PhD
Mariana.Figueiro@mountsinai.org
518-366-9306
Time Frame
Start Date: 2023-02-13
Estimated Completion Date: 2027-06-30
Participants
Target number of participants: 200
Treatments
Active_comparator: Circadian Effective Lighting (CEL)
The CEL will be performed in hospital sites over a 2-month period.
Sham_comparator: Circadian Ineffective Lighting (CIL)
The comparator lighting will be performed identical to Arm 1, at specified lower levels of lighting.
Sponsors
Leads: Icahn School of Medicine at Mount Sinai

This content was sourced from clinicaltrials.gov

Similar Clinical Trials