Bone Marrow Transplant Clinical Trials

Clinical trials related to Bone Marrow Transplant Procedure

Efficacy of High-Level Laser Therapy in Managing Oral Mucositis Among Pediatric Patients Undergoing Hematopoietic Stem Cell Transplantation: A Randomized Controlled Clinical Trial

Status: Recruiting
Location: See location...
Intervention Type: Drug, Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The goal of this clinical trial is to learn if high-level laser therapy can manage oral mucositis in pediatric patients undergoing hematopoietic bone marrow transplantation. The main question it aims to answer is : Is high-level laser therapy effective as a treatment for oral mucositis in pediatric hemopoietic stem cell transplant patients? Researchers will compare patients receiving basic oral care to see the effect on the WHO oral mucositis scale. Participants will be subjected to high level laser on lesion sites .

Eligibility
Participation Requirements
Sex: All
Maximum Age: 18
Healthy Volunteers: f
View:

• Children under the age of 18 years undergoing bone marrow transplantation during the phase of oral mucositis.

• Oral mucositis starting from grade II on the WHO scale for OM.

• Willingness to undergo treatment for four consecutive days and to return for evaluation 7 and 11 days after enrolment.

Locations
Other Locations
Egypt
Oncology and Bone marrow transplant unit, Children's hospital, Ain Shams University
RECRUITING
Cairo
Contact Information
Primary
Asmaa Ayman Gabr, Teaching Assistant
Asmaagabr@dent.asu.edu.eg
+2 01095692889
Time Frame
Start Date: 2025-06-15
Estimated Completion Date: 2030-12
Participants
Target number of participants: 14
Treatments
Experimental: High power laser therapy group
Pediatric bone marrow transplantation patients with oral mucositis will receive high-power laser therapy once daily for four consecutive days. The laser parameters will be a wavelength of 660 to 970 nm, of power 3.2 w, pulsed at 50% duty cycle, spot size of 1 cm2, for 230 sec, defocused mode.
Active_comparator: Basic oral care group
Pediatric bone marrow transplantation patients with oral mucositis will receive standard basic oral care. Local methods: mouth rinse chlorohexidine three times a day, sodium bicarbonate mouthwash.
Sponsors
Leads: Ain Shams University

This content was sourced from clinicaltrials.gov