Efficacy of Dexamethasone Versus Metoclopramide for Prophylaxis of Nausea and Vomiting After Cataract Surgery: A Double-blind Randomized Controlled Study

Status: Recruiting
Location: See location...
Intervention Type: Drug, Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Postoperative nausea and vomiting (PONV) is a common consequence of ambulatory surgery, affecting up to 80% of high-risk patients and 20-30% overall. Despite being widespread, a prior survey found that patients are more averse to PONV than pain and other significant postoperative problems. Furthermore, even mild cases of PONV can have serious repercussions, such as postanesthesia care unit (PACU) workflow disruption, delayed discharges, higher medical costs, and lower patient satisfaction.PONV following intraocular surgery can be unpleasant and may lead to serious complications including suprachoroidal hemorrhage (SCH). SCH is a potentially serious condition that occurs when the posterior ciliary arteries or vortex veins burst, resulting in blood in the suprachoroidal region. The hypothesis is that dexamethasone will lower the incidence of PONV after cataract surgery when compared with metoclopramide.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 40
Maximum Age: 80
Healthy Volunteers: f
View:

• Age: 40-80 years, both sexes.

• ASA physical status class I to III.

Locations
Other Locations
Egypt
Alexandria University
RECRUITING
Alexandria
Contact Information
Primary
sarah m elgamal, MD
sarahelgamal1990@yahoo.com
01005496440
Backup
moutaz ghandour, MD
Time Frame
Start Date: 2025-05-01
Estimated Completion Date: 2025-12-01
Participants
Target number of participants: 210
Treatments
Placebo_comparator: group p
patients will receive 0.9% normal saline
Active_comparator: group M
patients will receive 10 mg metoclopramide
Active_comparator: group D
patients will receive 8 mg dexamethasone
Related Therapeutic Areas
Sponsors
Leads: Alexandria University

This content was sourced from clinicaltrials.gov