Pregabalin Versus Dexmedetomidine for Delirium Treatment After Coronary Artery Bypass Grafting: A Randomized Double-Blind Trial
Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 4
SUMMARY
The aim of this study is to determine the effect of pregabalin versus dexmedetomidine on the treatment and lasting duration of delirium in fast tracking elderly patients after Coronary Artery Bypass Grafting.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 65
Healthy Volunteers: f
View:
• CABG patients ≥ 65 years of age both genders American Society of Anesthesiologists (ASA) physical status classification II or III planned for fast track developed postoperative delirium (POD).
Locations
Other Locations
Egypt
Islam Morsy
RECRUITING
Tanta
Contact Information
Primary
Islam Morsy, MD
eslam.morsy@med.tanta.edu.eg
00201093387374
Time Frame
Start Date: 2022-12-15
Estimated Completion Date: 2026-05-15
Participants
Target number of participants: 70
Treatments
Active_comparator: Pregabalin group
Patients will receive pregabalin capsules (75 mg) every 12 h for 24 hours by nasogastric tube.
Active_comparator: Dexmedetomidine group
Patients will receive a bolus dose of 0.4 μg/kg dexmedetomidine (over a period of 10 to 20 min) followed by an infusion of 0.2 to 0.7 μg/h.
Related Therapeutic Areas
Sponsors
Leads: Tanta University