A Single Centre Study Comparing Continuous Interstitial Fluid Lactate Detection (as Measured by Change in Current) to Standard Measurements of Change in Venous and Arterial Lactate in Patients Undergoing Elective Coronary Artery Bypass Graft Surgery and/or Valve Replacement.

Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The main goal of this study is to see if a wearable device can reliably track changes in lactate levels in the body. We\'ll compare the device\'s readings to standard blood tests to ensure accuracy. If successful, this device could reduce the need for frequent blood tests during surgery recovery, making patients more comfortable. It might also be useful in emergency rooms for quick diagnoses, especially for patients with chest pain. This study will take place at Barts Hospital with patients having planned coronary artery bypass graft (CABG) and/or replacement valve surgery. Participants will wear the sensors on their upper arm, during which the sensors will continuously measure lactate levels. Participants will also have hourly blood samples taken. In the future, the data from this new device will be used to train computer algorithms to provide quick responses that help manage a patient\'s condition, improving future medical care and technology.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 90
Healthy Volunteers: f
View:

• Able and willing to give informed consent

• ≥18 to ≤ 90 years old

• Successful surgery as defined by the below criteria (which will be recorded in the eCRF):

‣ Operative Success: The successful completion of coronary artery bypass grafting (CABG) and/or valve insertion with grafts and/or valves

⁃ Absence of the following complications:

⁃ Significant bleeding requiring reoperation

⁃ Evidence of major life-changing stroke

Locations
Other Locations
United Kingdom
Barts Health
RECRUITING
London
Contact Information
Primary
Prof Anthony Mathur
a.mathur@qmul.ac.uk
02037658740
Backup
Emily Kirkpatrick
e.kirkpatrick@qmul.ac.uk
Time Frame
Start Date: 2025-05-20
Estimated Completion Date: 2025-11-01
Participants
Target number of participants: 50
Treatments
Experimental: Investigational Lactate Device
Continuous interstitial fluid lactate monitoring using the Abbott Investigational Lactate Device
Sponsors
Leads: Queen Mary University of London

This content was sourced from clinicaltrials.gov