Effects of Pallidal Deep Brain Stimulation Location on Motor Impairment in Parkinson's Disease; Udall Project 2 Aims 1 & 2

Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

This protocol will characterize the effects of deep brain stimulation (DBS) location (both adverse and beneficial) on motor signs in people with Parkinson's disease (PD). This information can be used to inform future DBS protocols to tailor stimulation to the specific needs of a patient. If targeted dorsal GP stimulation is shown to significantly improve motor features that are typically resistant to dopamine replacement therapy, these experiments will likely have major impact on clinical practice by providing a potential strategy to these medically intractable symptoms.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 21
Maximum Age: 89
Healthy Volunteers: f
View:

• diagnosis of idiopathic PD

• have undergone neurosurgery to implant deep brain stimulators in the globus pallidus (GP DBS) or subthalamic nucleus (STN)

• Existing 7T brain imagery

Locations
United States
Minnesota
University Of Minnesota
RECRUITING
Minneapolis
Contact Information
Primary
Colum MacKinnon, PhD
cmackinn@umn.edu
Time Frame
Start Date: 2016-08-25
Estimated Completion Date: 2025-12-31
Participants
Target number of participants: 24
Treatments
Experimental: Parkinson's disease with DBS
Participants will have a diagnosis of idiopathic PD and have undergone/will undergo neurosurgery to implant deep brain stimulators in the globus pallidus (GP DBS) or subthalamic nucleus (STN)
Sponsors
Leads: University of Minnesota

This content was sourced from clinicaltrials.gov