Characterization of Subthalamic Nucleus Deep Brain Stimulation Laterality on Visuospatial Attention and Correlation to Freezing of Gait in Parkinson's Disease

Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The purpose of this research is to determine how deep brain stimulation (DBS) for Parkinson's disease affects attention and visuospatial function. Additionally, this study will evaluate how deficits in visual attention are associated with freezing of gait (FOG) in Parkinson's disease. There is currently no reliable treatment for FOG and little is understood about the underlying reason this occurs. Some recent research has found that stimulating the right side of the brain seems to improve FOG. The right side of the brain is also paramount for visual attention, which is why investigators are conducting this study.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Subjects above 18 years of age

• Subjects with freezing of gait

• Subjects with bilateral STN-DBS surgery as part of their clinical care for Parkinson's disease

Locations
United States
South Carolina
Medical University of South Carolina
RECRUITING
Charleston
Contact Information
Primary
Nathan DeTurk, MD
deturk@musc.edu
843-792-3221
Time Frame
Start Date: 2025-04-01
Estimated Completion Date: 2026-06
Participants
Target number of participants: 12
Treatments
Active_comparator: Left STN-DBS on, right STN-DBS off first
STN-DBS will be turned off sequentially for each side, in this group beginning with left STN-DBS on and right STN-DBS off. This will then be followed by the corollary.
Active_comparator: Right STN-DBS on, left STN-DBS off first
STN-DBS will be turned off sequentially for each side, in this group beginning with right STN-DBS on and left STN-DBS off. This will then be followed by the corollary.
Sponsors
Leads: Medical University of South Carolina

This content was sourced from clinicaltrials.gov