Deep Brain Stimulation Neural Recordings of Varied Stimulation During Sleep in Parkinson's Disease - The DREAMS-PD Study
This study employs an exploratory, prospective, single center, naturalistic clinical trial design with a randomized crossover intervention.
• Male or female \> 18 years of age
• Diagnosed with idiopathic Parkinson Disease
• Have bilateral implantation of Medtronic's PerceptTM PC (Medtronic Neurological Division, Minneapolis, MN, USA) Deep Brain Stimulation (DBS) system targeting the subthalamic nucleus (STN) and have had their stimulation settings optimized for a minimum of three months
• Report a response score of one or greater on question 1.7 of the Movement Disorder Society Unified Parkinson's Disease Rating Scale (MDS-UPDRS) part I;
• Demonstrate ability to ambulate independently;
• Be capable of providing informed consent;
• If taking sleep-supporting medications, dosing must be stable for at least 30 days