Nasal Outcomes Using Saline Irrigations After Endonasal Pituitary Surgery - The NOSE Trial
This is a prospective, single-blinded, multicenter study evaluating the benefit of sinonasal irrigations following endoscopic pituitary surgery. The goal of this study is to create practice changing guidelines with objective data highlighting the importance of irrigations on postoperative outcomes for pituitary surgery.
• Adult patient undergoing endoscopic surgery for resection of pituitary tumors
‣ nonfunctioning adenoma
⁃ acromegaly
⁃ prolactinoma
⁃ Rathke's cleft cyst
• Adults \>18 and \<85 years of age
• English speaking and able to understand the ASK Nasal-12 and SNOT-22 scales
• Free of any physical, mental, or medical condition which, in the opinion of the investigator, makes study participation inadvisable
• Planned binostril surgical approach
• Either with or without septal flap reconstruction
• Either with or without septoplasty