Efficacy of Prophylactic Epinephrine Solution Injection in Prevention of Delayed Post-sphincterotomy Bleeding in Patients with Transient Bleeding During ERCP
Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
Bleeding is the most frequently reported serious complication of endoscopic sphincterotomy, and severe bleeding has occurred in about 1% to 2% of patients. Endoscopic injection of epinephrine is the most commonly used, effective, and least expensive method for the management of post- sphincterotomy bleeding. However, the efficacy of prophylactic saline-epinephrine solution injection to prevent delayed EST bleeding when transient bleeding During ERCP has not been established.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 20
Healthy Volunteers: f
View:
• Age 20 years or older.
• Ability to give informed consent.
• An naive major papilla.
• Transient bleeding after endoscopic sphincterotomy
• Bleeding less than 30 secs when end of procedure
Locations
Other Locations
Taiwan
China Medical University Hospital
RECRUITING
Taichung
Contact Information
Primary
Shih-Chieh Chuang, MD
D18114@mail.cmuh.org.tw
+886-975680839
Backup
Wen-Hsin Huang, MD
u97766.huang@msa.hinet.net
+886-4-2205-2121
Time Frame
Start Date: 2021-07-15
Estimated Completion Date: 2030-12
Participants
Target number of participants: 400
Treatments
Experimental: Epinephrine solution injection group
In injected group, The saline epinephrine solution (1mg in 10ml N/S) is injected to 2 sites of cutted papilla (1 o'clock and 11 o'clock) by injected needle, at least 0.5ml per injected site, and must be protruded from submucosal layer.
No_intervention: non-injection group
In non injection group, the saline epinephrine solution is not given
Related Therapeutic Areas
Sponsors
Leads: Wen-Hsin Huang