Prediction of Drug-Induced Sleep Endoscopy Outcome From Baseline Diagnostic Data Including Polysomnography

Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Observational
SUMMARY

The study is designed to develop models to predict site of collapse information using routine polysomnography. In an observational study, the investigators will study 1000 patients with obstructive sleep apnea (OSA) who have had a recent polysomnographic study and will undergo drug-induced sleep endoscopy (DISE) as part of their standard clinical care. Flow shape information from the polysomnographic study will be associated with the DISE results, and a set of prediction models will be developed and validated to detect the site, pattern and degree of upper airway collapse as seen during DISE.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• 18 years or older.

• Diagnosis with OSA (AHI ≥ 5).

• Eligible for drug-induced sleep endoscopy as the next step in the clinical path for OSA.

• Capable of giving informed consent.

Locations
Other Locations
Belgium
Antwerp University Hospital
RECRUITING
Edegem
Contact Information
Primary
Sara Op de Beeck, PhD
sara.opdebeeck@uza.be
0032 3 821 3385
Time Frame
Start Date: 2022-02-01
Estimated Completion Date: 2026-01
Participants
Target number of participants: 1000
Treatments
Obstructive sleep apnea patients eligible for DISE
Patients with obstructive sleep apnea (AHI\>=5) will be included in the study. Subjects should be eligible for drug-induced sleep endoscopy as the next step in their clinical path.
Related Therapeutic Areas
Sponsors
Leads: University Hospital, Antwerp
Collaborators: Universiteit Antwerpen

This content was sourced from clinicaltrials.gov