Propofol and Etomidate Admixtures Comparisons Trial (PEAC Trial)
Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 3
SUMMARY
The purpose of this study is to evaluate the hemodynamics and adverse event profile in comparison between two treatment arms, one using an admixture of propofol and etomidate at a ratio by volume of 25%/75% (P2E7), and one using an admixture of propofol and etomidate at a ratio by volume of 75%/25% (P7E2), for anesthesia during endoscopic procedures at the Clements University Hospital (CUH) endoscopy lab (Endo).
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Adult patients (age ≥18 years old)
• Having endoscopic procedure at CUH with anesthesia
• ASA 3 or above
• Ejection Fraction test result available
Locations
United States
Texas
Clements University Hospital
RECRUITING
Dallas
Contact Information
Primary
Christopher Choi
christopher.choi@utsouthwestern.edu
2146486400
Backup
Kapil Anand
kapil.anand@utsouthwestern.edu
2146486400
Time Frame
Start Date: 2022-09-19
Estimated Completion Date: 2025-09
Participants
Target number of participants: 200
Treatments
Experimental: Admixture of propofol and etomidate at a ratio by volume of 75%/25% (P7E2)
This a prospective double blind randomized controlled clinical trial. The purpose of this study is to evaluate the hemodynamics and adverse event profile in comparison between two treatment arms, one using an admixture of propofol and etomidate at a ratio by volume of 25%/75% (P2E7), and one using an admixture of propofol and etomidate at a ratio by volume of 75%/25% (P7E2), for anesthesia during endoscopic procedures at the Clements University Hospital endoscopy lab.
Experimental: Admixture of propofol and etomidate at a ratio by volume of 25%/75% (P2E7)
This a prospective double blind randomized controlled clinical trial. The purpose of this study is to evaluate the hemodynamics and adverse event profile in comparison between two treatment arms, one using an admixture of propofol and etomidate at a ratio by volume of 25%/75% (P2E7), and one using an admixture of propofol and etomidate at a ratio by volume of 75%/25% (P7E2), for anesthesia during endoscopic procedures at the Clements University Hospital endoscopy lab.
Related Therapeutic Areas
Sponsors
Leads: University of Texas Southwestern Medical Center