EEG to Monitor Propofol Anesthetic Depth in Infants and Toddlers
The goal of this study is monitor anesthetic depth of children undergoing propofol anesthesia using electroencephalography (EEG). The main questions it aims to answer are: 1. EEG spectral edge frequency (SEF95) readings where 50% of patients do not respond to three stimuli. 2. The propofol blood concentration that corresponds to each of the three EEG SEF95 readings Participants will undergo EEG monitoring, stimuli (placement of oral pacifier, electrical stimulation, and laryngoscopy), and blood collection.
• Children 3 to 24 month old undergoing surgery.
• Planned laryngoscopy and endotracheal intubation or laryngeal mask airway (LMA) placement for clinical care.
• Planned propofol anesthesia for anesthesia maintenance.
• American Society of Anesthesiologists (ASA ) \< III.
• Muscle relaxant not indicated per planned clinical care for laryngoscopy/intubation or LMA.
• Anticipated surgery duration approximately \< 2h40min