Narrow Band Imaging Versus White Light for the Detection and Miss of Sessile Serrated Lesions：a Multicenter，Random，Back-to-back Trial
Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
Narrow band imaging(NBI) could improve the detection of colorectal lesions, previous investigations demonstrated its potential in detecting not only colorectal adenoma but non-adenomatous polyps, including sessile serrated lesions. But no randomized controlled trials with NBI versus white light imaging(WLI) have been conducted to give a definitive conclusion with statistically significant differences. Therefore, we performed a multicenter, prospective, back to back, randomized controlled trial to compare sessile serrated lesions detection and miss rate of withdraw by NBI and WLI in colonoscopy.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 45
Maximum Age: 85
Healthy Volunteers: f
View:
• Patients whose age are between 45-85
• Patients who have indications for screening
• Patients who have signed inform consent form.
Locations
Other Locations
China
Changhai Hospital, Second Military Medical University
RECRUITING
Shanghai
Contact Information
Primary
Zhaoshen Li, MD
li.zhaoshen@hotmail.com
86-021-31161365
Backup
Yu Bai, MD
baiyu1998@hotmail.com
86-021-31161335
Time Frame
Start Date: 2023-02-01
Estimated Completion Date: 2024-05-28
Participants
Target number of participants: 840
Treatments
Experimental: WLI Then NBI Withdrawal Group
After successful intubation of the cecum, carefully inspect the whole colorectal mucosa by white light imaging(WLI) during the first colonoscopy withdraw. Then reinsert to the cecum and withdraw with narrow band imaging(NBI). Stop watch will be utilized to remind endoscopists.
Active_comparator: NBI Then WLI Withdrawal Group
After successful intubation of the cecum, carefully inspect the whole colorectal mucosa by narrow band imaging(NBI) during the first colonoscopy withdraw. Then reinsert to the cecum and withdraw with white light imaging(WLI). Stop watch will be utilized to remind endoscopists.
Related Therapeutic Areas
Sponsors
Collaborators: 900 Hospital of Joint Logistics Support Force of PLA, Ankang Central Hospital, Chongqing General Hospital, The Second Hospital of Hebei Medical University, Qilu Hospital, Shandong University, Yantaishan Hospital, Shandong First Medical University, Air Force Military Medical University, China, The Second Affiliated Hospital of Baotou Medical College, The First Affiliated Hospital of Dalian Medical University, Heilongjiang provincial hospital, Haikou People's Hospital, Huadong Hospital, Tengzhou Central People's Hospital, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Nongken Jiansanjiang People Hospital of Heilongjiang Province
Leads: Changhai Hospital