Comparison of Intubation Conditions During Rapid Sequence Induction Obtained With Modified Time Principal Induction With a Standard Intubation Dose of Rocuronium Versus Succinylcholine : A Prospective Non-inferiority Randomized and Blind Trial

Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 4
SUMMARY

The purpose of this study is to assess and compare conditions for tracheal intubation obtained with modified time principal induction with 0.6 mg/kg rocuronium and 1 mg/kg succinylcholine. Specifically, the investigators will be evaluating ease of laryngoscopy, vocal cord view, vocal cord opening, and movement of limbs and coughing during tracheal intubation in order to assess intubation conditions, to compare efficiency and success rate of tracheal intubation between two induction agents and to determine the rate of patient awareness during induction and post-operative recall of paralysis.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• BMI \> 30kg/m2 or Mallampati class III or IV.

• Requiring general anesthesia and endotracheal intubation

Locations
United States
Texas
The University of Texas Health Science Center at Houston
RECRUITING
Houston
Contact Information
Primary
Lauren M Nakazawa, MD,MBA
Lauren.M.Nakazawa@uth.tmc.edu
713-500-6775
Backup
Ellie Tuchaai
Ellie.J.Tuchaai@uth.tmc.edu
713.614.9355
Time Frame
Start Date: 2023-09-13
Estimated Completion Date: 2025-07-01
Participants
Target number of participants: 152
Treatments
Experimental: Modified Time Principle Induction (MTPI) with rocuronium
Active_comparator: RSI with succinylcholine
Related Therapeutic Areas
Sponsors
Leads: The University of Texas Health Science Center, Houston

This content was sourced from clinicaltrials.gov