Does Intravenous Lidocaine Reduce ED 50 for Propofol Administered Using Target Controlled Infusion (TCI) During Gastroscopy in ASA 1 and 2 Patients.
Status: Recruiting
Location: See location...
Intervention Type: Drug, Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The goal of this prospective, interventionnal clinical trial is to assess if intravenous administration of linisol reduce the ED50 of propofol when administered using Target Controlled Infusion (TCI) during gastroscopy in healthy patients (ASA 1 and 2 patients). Prior to propofol sedation, participants will receive either an intravenous bolus of linisol (1.5 mg/kg) = treated group or placebo = control group.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 65
Healthy Volunteers: f
View:
• Patients scheduled for gastroscopy under narcosis and who have signed the consent.
• ASA score: 1 and 2
• BMI between 18 and 30 kg/m2
Locations
Other Locations
Belgium
Boudart Céline
RECRUITING
Brussels
Contact Information
Primary
Céline Boudart, PhD
celine.boudart@hubruxelles.be
+322555391+9
Time Frame
Start Date: 2024-04-08
Estimated Completion Date: 2024-08-31
Participants
Target number of participants: 50
Treatments
Active_comparator: Linisol
Patients will receive 1.5 mg/kg of intravenous linisol before propofol sedatation and gastroscope introduction
Placebo_comparator: Control
Patients will receive intravenous placebo (saline solution),before propofol sedation and gastroscope introduction
Related Therapeutic Areas
Sponsors
Leads: Erasme University Hospital