Regression of Cervical Precancerous Lesions and Associated Risk Factors
Status: Recruiting
Intervention Type: Diagnostic test
Study Type: Observational
SUMMARY
The aim of this study is to assess the extent of histopathological regression of severe cervical precancerous lesions (CIN 2 and CIN 3); evaluate the proportion of patients who experience the normalization of HPV test and cytology finding among those who were treated conservatively and those who underwent conization; and identify predictive parameters associated with regression. Based on this analysis, a model will be proposed to predict the likelihood of lesion regression.
Eligibility
Participation Requirements
Sex: Female
Minimum Age: 18
Maximum Age: 40
View:
• squamocolumnar junction fully visualized
• bioptically verified CIN 2 or CIN 3
• age ≥ 18 years
• informed consent
Contact Information
Primary
Lukas Dostalek
lukas.dostalek@vfn.cz
+420224967451
Time Frame
Start Date: 2022-09-01
Estimated Completion Date: 2027-07-01
Participants
Target number of participants: 300
Treatments
CIN 2, CIN 3
Bioptically verified CIN 2 or CIN 3 lesion
Related Therapeutic Areas
Sponsors
Leads: General University Hospital, Prague