Timing of Resumption of Direct Oral Anticoagulants Following Colonoscopy Polypectomy: a Prospective Randomized Non-inferiority Trial
Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The goal of this prospective randomized non-inferiority trial is to compare two different resumption time of Direct Oral Anticoagulants (DOACs) after colonoscopic polypectomy. We hypothesize that early resumption of DOACs after colonoscopy and polypectomy is associated with comparable post-polypectomy bleeding rate to those with delayed resumption. This study aims to compare the post-polypectomy bleeding risk of two different timing of resuming DOACs (Day 0 vs Day 2):
Eligibility
Participation Requirements
Sex: All
Minimum Age: 40
Healthy Volunteers: f
View:
• \- All adult patients who are taking DOACs and schedule for elective colonoscopy are potentially eligible. We only included patients who had complete colonoscopy and with polypectomy performed.
Locations
Other Locations
Hong Kong Special Administrative Region
Queen Mary Hospital, the University of Hong Kong
RECRUITING
Hong Kong
Contact Information
Primary
Wai Keung Leung
waikleung@hku.hk
+852 22553348
Time Frame
Start Date: 2024-10-03
Estimated Completion Date: 2026-12-31
Participants
Target number of participants: 194
Treatments
Active_comparator: Late Resumption
The first group will recommence DOACs on Day 2 as recommended by current guideline (Late Resumption)
Experimental: Early Resumption
The second group will resume DOACs on the same day of the procedure (Early Resumption).
Related Therapeutic Areas
Sponsors
Leads: The University of Hong Kong