Understanding the Variation of Modern Endoscopic Ultrasound Use in Patients with Oesophageal Cancer (VALUE): a Multi-methods Study

Status: Recruiting
Location: See all (8) locations...
Intervention Type: Procedure
Study Type: Observational
SUMMARY

This is an observational trial that will look at patients undergoing endoscopic ultrasound (EUS) in patients with oesophageal cancer and to determine the proportion of cases in which EUS changes disease management in these patients.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 16
Healthy Volunteers: f
View:

• Patients aged 16 or above with first diagnosis of biopsy-confirmed oesophageal cancer.

• Referred for EUS examination as part of standard of care investigations.

• Tumour location in the oesophagus, or gastro-oesophageal junction (Siewert types I-III)

• MDT decision that patient is potentially curable with radical treatment (e.g., endoscopic treatment, surgery +/- neoadjuvant therapy, or definitive chemoradiotherapy)

• Prior staging with CT and PET-CT

• Eastern Cooperative Oncology Group (ECOG) performance status 0-2

• Clinical staging of T1-T4, N0-N3, M0 disease

• Adenocarcinoma or squamous cell carcinoma (SCC) histopathological cell type

Locations
Other Locations
United Kingdom
Royal Bournemouth Hospital
NOT_YET_RECRUITING
Bournemouth
Cambridge University NHS Foundation Trust
NOT_YET_RECRUITING
Cambridge
Velindre University NHS Trust
NOT_YET_RECRUITING
Cardiff
Glasgow Royal Infirmary
NOT_YET_RECRUITING
Glasgow
Castle Hill Hospital
RECRUITING
Hull
Imperial College Healthcare NHS Trust
NOT_YET_RECRUITING
London
University Hospital Southampton
RECRUITING
Southampton
Royal Cornwall Hospital
NOT_YET_RECRUITING
Truro
Contact Information
Primary
Ben Lindfield
value@soton.ac.uk
023 8120 5154
Time Frame
Start Date: 2024-06-27
Estimated Completion Date: 2026-06-30
Participants
Target number of participants: 180
Related Therapeutic Areas
Sponsors
Leads: University Hospital Southampton NHS Foundation Trust
Collaborators: National Institute for Health Research, United Kingdom

This content was sourced from clinicaltrials.gov