Does Non-Steroidal Anti-inflammatory Drugs Decrease the Quality of Pleurodesis After Mechanical Pleural Abrasion/Pleurectomy for Treatment of Pneumothorax?
Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 1/Phase 2
SUMMARY
Investigators aim to assess if NSAIDs affect the quality of pleurodesis resulting from mechanical pleurodesis (open surgery or VATS) regarding : Primary outcome: Recurrence of pneumothorax in 6 monthes. (assessed by X ray after 2 weeks and 6 months or symptoms requiring X ray at any timing) Secondary outcome: ▪ Adjusted Length of stay ( from day zero surgery day to discharge ). ▪ Time of removal of the chest Tube .(relatively longer with air leak presence). ▪ Need of opioids (N-SAID may decrease the need of opioids) .
Eligibility
Participation Requirements
Sex: All
Healthy Volunteers: t
View:
• Patients presented with primary or secondary spontaneous pneumothorax
• Age: All age groups are included
• Approach: Open and Video assisted thoracoscopic surgery ( Open and VATS pleurodesis).
Locations
Other Locations
Egypt
Faculty of medicine, Ain shams university
RECRUITING
Cairo
Contact Information
Primary
Hany Hassan, Professor
hanyhassan77@hotmail.com
+201227373270
Time Frame
Start Date: 2023-09-01
Estimated Completion Date: 2024-12
Participants
Target number of participants: 116
Treatments
Active_comparator: Participants post mechanical pleurodesis taking classic pain management with NSAID
Active_comparator: Participants post mechanical pleurodesis taking classic pain management without NSAID
Related Therapeutic Areas
Sponsors
Leads: Ain Shams University