Development and Evaluation of an Artificial Intelligence Model for Cervical Cancer Detection From Colposcopic Images

Status: Recruiting
Location: See location...
Intervention Type: Diagnostic test
Study Type: Observational
SUMMARY

Cervical cancer is a significant health issue, particularly in low-income countries, where late diagnosis and limited access to screenings contribute to high mortality rates. This study aims to develop and evaluate an artificial intelligence (AI) model to analyze colposcopic images for detecting cervical cancer more accurately and efficiently. Colposcopy, a procedure used to examine the cervix for signs of cancer, relies heavily on doctors' expertise, leading to inconsistent results. The current gold standard, colposcopy-directed biopsy, is invasive and can cause complications. The hypothesis is that an AI model can outperform traditional methods in identifying cervical abnormalities, providing a reliable and scalable solution for early detection, especially in underserved areas. By automating the analysis process, the AI model aims to reduce reliance on trained personnel, making cervical cancer screening more accessible and improving early diagnosis and treatment outcomes. The study will create a diverse dataset of colposcopy images from various sources and develop the AI model. The model's performance will be validated in clinical settings, assessing its accuracy in classifying cancer stages and identifying transformation zones. The impact on early detection, patient outcomes, and model usability will be evaluated, as well as its generalizability across different healthcare environments. The goal is to enhance the accuracy and efficiency of cervical cancer screening, ultimately reducing mortality rates and improving patient care.

Eligibility
Participation Requirements
Sex: Female
Minimum Age: 18
Healthy Volunteers: t
View:

• Female patients of age 18 years or older can be selectedas subjects.

• Individuals willing to participate in cervical cancerscreening.

• Availability for colposcopic examination.

• Women with no history of hysterectomy (total removalof the uterus).

• Women with no current or prior diagnosis of cervicalcancer.

• Availability of relevant medical records forconfirmation and comparison purposes.

Locations
Other Locations
Bangladesh
Ibn Sina Medical College Hospital
RECRUITING
Dhaka
Contact Information
Primary
Taufiq Hasan, PhD
taufiq@bme.buet.ac.bd
+8801817579844
Backup
Raiyun Kabir, B.Sc.
razeenraiyun99@gmail.com
+8801521525834
Time Frame
Start Date: 2024-01-11
Estimated Completion Date: 2025-02-11
Participants
Target number of participants: 500
Treatments
Self reported uterine distress undergoing colposcopic evaluation
The study group consists of women undergoing cervical cancer screening. This includes those with suspected cervical abnormalities identified through initial cytology or HPV tests and referred for colposcopy. The study group also includes women without apparent cervical abnormalities to ensure a comprehensive dataset. The aim is to develop an AI model capable of accurately diagnosing cervical cancer and identifying transformation zones in colposcopic images. This diverse group allows for the evaluation of the AI model across a wide range of conditions and exposures, enhancing its generalizability and clinical utility.
Related Therapeutic Areas
Sponsors
Leads: Bangladesh University of Engineering and Technology

This content was sourced from clinicaltrials.gov

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